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Comptonia peregrina
No specific contraindications in available data.
No information on dermal reactions for sweet fern oil, but based on composition (high β-caryophyllene, no carcinogens), risk is likely low.
A β-caryophyllene-rich fraction showed anticarcinogenic activity against human lung and colon cancer cells in vitro.
| β-Caryophyllene | 24.5 % |
| 1,8-Cineole | 6.0 % |
| β-Myrcene | 5.1 % |
| δ-Cadinene | 4.2 % |
| (E)-Nerolidol | 3.7 % |
| α-Caryophyllene | 3.0 % |
| Linalool | 2.6 % |
| γ-Terpinene | 2.5 % |
| γ-Cadinene | 2.2 % |
| α-Pinene | 2.2 % |
| β-Selinene | 2.1 % |
| β-Chamigrene | 1.7 % |
| Caryophyllene oxide | 1.5 % |
Comptonia peregrina is a small shrub of northeastern North America. Despite the 'fern' name, this is not a true fern but a dicot in the same family as myrtle and sweet gale.
The oil is steam-distilled from the leaves. Limited availability.
Family Myricaceae.