Clove bud

Drug interactions. May contain methyleugenol. May inhibit blood clotting. Embryotoxic. Moderate risk of skin and mucous membrane sensitization.

Oral: pethidine, MAOIs, SSRIs, anticoagulant medication, before major surgery, peptic ulcer, hemophilia.

Dermal: avoid on hypersensitive, diseased or damaged skin, and on children under 2 years.

Maximum dermal use level 0.5 percent based on 96.9 percent eugenol and a dermal limit of 0.5 percent.

Three reports of oral poisoning in children (5 to 10 mL ingested) caused acidosis, liver failure, coma. No deaths but near-fatal.

Skin contact with undiluted clove oil frequently produces a burning sensation and occasional blistering.

Syzygium aromaticum is a tree native to the Maluku Islands of Indonesia. The dried flower buds are the spice clove used in cuisine worldwide.

Main production in Indonesia, Madagascar and Tanzania. Indonesia consumes much of its output for local kretek cigarettes.

Family Myrtaceae. Among the three clove oils (bud, leaf, stem), bud is the highest-priced and most refined in aroma.

May be adulterated with clove stem oil, clove leaf oil, or eugenol.