Atractylis

Drug interaction.

May be fetotoxic (based on β-elemene and β-eudesmol content).

May inhibit blood clotting.

No skin irritation data for atractylis oil. Composition does not suggest high risk.

β-Eudesmol inhibits platelet aggregation.

Contraindicated all routes: pregnancy and lactation.

Plant in the Asteraceae family, native to East Asia — China, Japan, Korea.

In Traditional Chinese Medicine (Cang-zhu), the root is used for digestive disorders and joint pain.

Oil extracted from roots.

β-Elemene and β-eudesmol have antiangiogenic activity — basis for the fetotoxicity warning.

Although toxicity of some constituents is unknown, the overall profile does not suggest major risks beyond the pregnancy contraindication.