Araucaria

Drug interaction.

May be fetotoxic (based on β-eudesmol content).

May inhibit blood clotting.

β-Eudesmol inhibits platelet aggregation — essential step in clotting cascade.

Guaiol and β-eudesmol have hypotensive effects.

Contraindicated all routes: pregnancy and lactation.

Tree native to New Caledonia (South Pacific).

Listed on IUCN — International Union for Conservation of Nature — threatened species list.

Very limited availability.

γ-Eudesmol displays anticarcinogenic activity. β-Eudesmol has antiangiogenic activity — which is also the basis for the fetotoxicity warning.