2-(1-Methylethyl)-5-methylcyclohexanone
2-Isopropyl-5-methylcyclohexanone · p-Menthan-3-one
化学組成 · Constituent
Isomenthone is a monoterpenoid ketone isomeric with menthone, occurring substantially in pennyroyal, buchu, cornmint and peppermint.
Skin. An 8 percent patch test on 25 volunteers produced neither irritation nor sensitization.
Oral and dermal. Acute dermal LD50 in rats exceeds 5 g/kg.
Antioxidant. Significant radical scavenging activity against DPPH and OH.
| Pennyroyal | 0.8 – 31.0 % |
| Buchu (diosphenol CT) | 4.6 – 29.1 % |
| Buchu (pulegone CT) | 3.6 – 27.6 % |
| Cornmint | 6.8 – 12.1 % |
| Geranium | 3.4 – 9.8 % |
| Peppermint | 2.0 – 8.7 % |
| Calamint (lesser) | 0 – 2.8 % |
| Cistus | 0 – 2.3 % |
Isomenthol is the major and possibly the only urinary metabolite of isomenthone detected in rabbit urine.
Isomenthone is a secondary constituent in the Mentha family, contributing to the overall mint profile alongside menthone, menthol and pulegone.