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Neryl acetate

(Z)-3,7-Dimethyl-2,6-octadien-1-yl ethanoate

Acetic acid neryl ester

Aliphatic monoterpenoid alkene ester · C₁₂H₂₀O₂

Chemical structure of Neryl acetate
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
141-12-8
Molecular formula
C₁₂H₂₀O₂
Molecular weight
196.29 g/mol
Aroma
Rose floral, sweetly soft, lightly herbaceous. A main note in helichrysum.

Safety

Low concern · Safe at standard use

Neryl acetate is the dominant ester of helichrysum (immortelle), present at high levels in several chemotypes.

Skin. Undiluted neryl acetate was non-irritating to rabbit skin. A 10 percent test on 25 volunteers caused no irritation and no sensitization.

Acute toxicity. Acute oral LD50 in rats exceeded 5 g/kg. Acute dermal LD50 in rabbits exceeded 5 g/kg.


Usage guidelines

Concern level
Low
Regulatory limit
No IFRA or EU limit set specifically

Found in essential oils

Principal sources
Helichrysum (immortelle)6.1 – 39.9 %
Fenugreek17.3 %
Lemon leaf3.7 – 7.4 %
Melissa1.5 – 4.0 %
Orange flower0.8 – 4.0 %
Linaloe wood2.5 %
Neroli0.3 – 2.1 %
Lemon balm (Australian)1.6 %
Lemon (expressed)0.1 – 1.5 %
Bergamot0.1 – 1.2 %
Skimmia1.1 %

Notes

Neryl acetate is the main marker for Helichrysum italicum subsp. microphyllum oil, used to distinguish this chemotype from the original helichrysum (which contains more italidiones).