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Methyl allyl trisulfide

Methyl 2-propenyl trisulfide

Allyl methyl trisulfide · 4,5,6-Trithia-1-heptene

Aliphatic alkene trisulfide · C₄H₈S₃

Chemical structure of Methyl allyl trisulfide
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
34135-85-8
Molecular formula
C₄H₈S₃
Molecular weight
152.30 g/mol
Aroma
Intense garlic, deeply sulfurous, sharp. A major sulfur constituent of garlic oil.

Safety

Limited data · Trace constituent

Methyl allyl trisulfide is a characteristic trisulfide of garlic oil. No published data on skin reactions or toxicity.

Cardiovascular. The compound inhibits platelet aggregation in vitro.

Anticancer activity. Methyl allyl trisulfide induced glutathione S-transferase in mouse forestomach, small intestine, liver and lung. Two doses of 15.0 µmol (2.3 mg) inhibited benzo[a]pyrene-induced forestomach tumors but not lung tumors.

Usage guidelines

Concern level
Limited data
Bioactivity
Antiplatelet, antitumoral

Found in essential oils

Principal sources
Garlic8.3 – 18.2 %

Notes

Methyl allyl trisulfide is more abundant in mature garlic oil through conversion from precursor disulfides. Oral garlic oil warrants caution alongside anticoagulant therapy.