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Guaiol

2-[(3S,5R,8S)-3,8-Dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]propan-2-ol

Guaiol, Champacol, Guaiac alcohol

Sesquiterpene alcohol (guaiane) · C₁₅H₂₆O

Chemical structure of Guaiol
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
489-86-1
Molecular formula
C₁₅H₂₆O
Molecular weight
222.37 g/mol
Origin
Natural
Odor family
Woody
Note
Base
Aroma
Sweet, light wood with a tea-rose nuance; weak.

History

Guaiol is a crystalline sesquiterpene alcohol and a main constituent of guaiacwood oil (Bulnesia sarmientoi). It also occurs in Callitris pine wood and other species.

In perfumery

Guaiol matters as a constituent of guaiacwood oil; in pure form it is acetylated to guaiyl acetate.

Connections

Evokesguaiacwood
Found in natureGuaiac wood (Bulnesia sarmientoi)

Regulatory status

Natural constituent · No IFRA standard
IFRA 51
No dedicated IFRA Standard in the 51st Amendment index.
EU allergen 2023/1545
Not named individually in the expanded allergen list of Regulation 2023/1545.

Sources

  1. NCI/CADD Chemical Identifier Resolver, CAS 489-86-1 (formula, names)
  2. Sell C.S. (ed.) The Chemistry of Fragrances: From Perfumer to Consumer, 2nd ed., Royal Society of Chemistry 2006
  3. The Good Scents Company Information System, material entries
  4. IFRA Standards, 51st Amendment: Index of IFRA Standards (notified 30 June 2023)