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Dodecyl acetate

n-Dodecyl ethanoate

n-Dodecyl acetate · Lauryl acetate · Acetic acid dodecyl ester

Aliphatic ester · C₁₄H₂₈O₂

Chemical structure of Dodecyl acetate
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
112-66-3
Molecular formula
C₁₄H₂₈O₂
Molecular weight
228.37 g/mol
Aroma
Lightly waxy, sweetly floral, with a fatty undertone.

Safety

Low concern · Safe at standard use

Dodecyl acetate is a long-chain ester found in a few floral essential oils.

Skin. Applied undiluted to rabbit skin, it was slightly irritating. A 20 percent patch test on 25 volunteers produced neither irritation nor sensitization.

Oral and dermal. Acute oral LD50 in rats and acute dermal LD50 in rabbits both exceed 5 g/kg.

Subchronic. Repeated application of high doses of undiluted material following DMBA initiation produced skin tumors in 3 of 15 mice. No tumors developed in a 33 percent solution group or in non-initiated mice.

Usage guidelines

Concern level
Low at standard use
Oils with high content
Boronia absolute 3.8 percent

Found in essential oils

Principal sources
Ambrette0.2 – 4.0 %
Boronia3.8 %

Notes

Dodecyl acetate is used as a waxy-floral note in perfumery at low concentrations.