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Massoia lactone

(R)-(-)-6-Pentyl-5,6-dihydro-2H-pyran-2-one

(-)-Massoia lactone · 2-Decen-5-olide

Monoterpenoid alkene lactone · C₁₀H₁₆O₂

Chemical structure of Massoia lactone
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
51154-96-2
Molecular formula
C₁₀H₁₆O₂
Molecular weight
168.23 g/mol
Aroma
Coconut cream, fatty and deeply sweet. The signature note of massoia oil.

Safety

Severely irritating · IFRA restricted

Massoia lactone is the dominant constituent of massoia oil. The compound is described as so irritating that standard sensitization and phototoxicity tests could not be conducted.

IFRA recommends that massoia lactone not be used as a fragrance ingredient. The compound merits further open and transparent investigation.

Safety recommendation. The proposed maximum dermal use level is 0.01 percent. Massoia oil is essentially unsuitable for topical applications.

Usage guidelines

Concern level
High, severe irritation
IFRA recommendation
Not recommended for fragrance use
Maximum dermal level
0.01 percent

Found in essential oils

Principal sources
Massoia68.2 %
Sage (wild mountain)1.4 %

Notes

Massoia lactone gives massoia oil its coconut cream aroma. In food and perfumery, the synthetic compound is used at extremely low concentrations.