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Lilial (butylphenyl methylpropional)

3-(4-tert-butylphenyl)-2-methylpropanal

Lilial, Butylphenyl methylpropional, p-BMHCA

Aromatic aldehyde · C₁₄H₂₀O

Chemical structure of Lilial (butylphenyl methylpropional)
2D structure PubChem / NCI CIR

Chemical info

CAS number CAS
80-54-6
Molecular formula
C₁₄H₂₀O
Molecular weight
204.31 g/mol
Origin
Synthetic
Odor family
Floral
Note
Heart
Aroma
Soft, clean lily of the valley, slightly powdery and melon-like; good diffusion.

History

Lilial was once among the most widely used muguet aldehydes in cosmetics and detergents. After classification as toxic for reproduction category 1B it was moved to Annex II and banned from cosmetics in the EU from 1 March 2022 under Regulation (EU) 2021/1902.


In perfumery

No longer used in cosmetics sold in the EU. Houses have replaced it with other muguet materials such as Florol, Mayol, Majantol or newer molecules.


Connections

EvokesLily of the valley

Regulatory status

Banned in EU
IFRA 51
Covered by an IFRA Standard (entry "p-tert-Butyl-alpha-methylhydrocinnamic aldehyde (p-BMHCA)"), current version issued at Amendment 49. The Standard text sets the applicable conditions.
EU CosReg
II, 1666: trong 1/3/2022. Annex II, entry 1666: prohibited in cosmetics, applicable from 1 March 2022.
EU allergen 2023/1545
Not on the list of fragrance allergens requiring labelling, including after Regulation (EU) 2023/1545.

Sources

  1. NCI/CADD Chemical Identifier Resolver, CAS 80-54-6
  2. IFRA Standards Library, Amendments up to 51
  3. Regulation (EC) No 1223/2009, consolidated text of 18.05.2026, Annexes II and III
  4. Commission Regulation (EU) 2021/1902 (CMR substances, Annex II)