[3R-(3α,3aβ,7β,8aα)]-Octahydro-3,8,8-trimethyl-6-methylene-1H-3a,7-methanoazulene
8(15)-Cedrene · Cedr-8(15)-ene
化学組成 · Constituent
β-Cedrene shares its toxicity profile with α-cedrene. Cedrene (unspecified isomer) by intraperitoneal, oral or inhalation routes significantly induces CYP and ethylmorphine N-demethylase, with potential to interact with opioids.
Oral 200 mg/kg/day for three days increased ethylmorphine metabolism by 160 percent and CYP by 40 percent. Inhalation 60 mg/kg/day for 2–6 days raised EMND by 180 percent.
Direct acute toxicity and skin sensitization data are sparse, but structural similarity to α-cedrene does not raise specific safety flags.
| Cedarwood (Virginian) | 8.2 – 9.2 % |
| Cedarwood (Texan) | 5.5 % |
| Hinoki leaf | 4.7 % |
| Cedarwood (Himalayan) | 1.4 % |
β-Cedrene is the minor isomer in cedarwood oils. The compound is typically analyzed alongside α-cedrene as an oil quality marker.